Adverse trends are identified as three or more similar major deviations within a rolling 6-month period across different sites so that potential issues can be addressed proactively.

Adverse Trends: Three or more similar major deviations within a rolling 6-month period across different sites. Adverse trends are identified as three or more similar major deviations. Three or more similar major deviations within a rolling 6-month period.

legacy import — synthesised from supporting_context_primary